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Article

Pathology of CAG repeat diseases

1 Dec 2000

Abstract excerpt

Neuronal intranuclear inclusions have become the neuropathological signature of the CAG repeat diseases, although their cytotoxicity is a matter of controversy. It has been demonstrated that the inclusions in dentatorubral-pallidoluysian atrophy (DRPLA) and Machado-Joseph disease (MJD) were immunopositive for several transcription factors such as TATA-binding protein (TBP), TBP-associated factor (TAF(II)130),...

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PMID: 11211058
DOI: 10.1046/j.1440-1789.2000.00354.x

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