Article
There is no evidence of an association in children and teenagers between the apolipoprotein E epsilon4 allele and post-traumatic brain swelling.
Neuropathology and applied neurobiology - 1 Dec 2004
Quinn T J, Smith C, Murray L, Stewart J, Nicoll J A R, Graham D I
Abstract excerpt
Traumatic brain injury (TBI) is an important cause of mortality and disability in children and teenagers. A particular feature of the neuropathology at post-mortem is brain swelling. The cause of the swelling in some cases is not known, while in others it is associated with traumatic axonal injury or hypoxia. Apolipoprotein E (APOE) epsilon4 allele is known to be an important genetic determinant of outcome in...
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