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Article

Multiple gastrointestinal stromal tumors in type I neurofibromatosis: a pathologic and molecular study.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2005

Yantiss Rhonda K, Rosenberg Andrew E, Sarran Lisa, Besmer Peter, Antonescu Cristina R

Abstract excerpt

Multiple gastrointestinal stromal tumors typically occur in familial form associated with KIT receptor tyrosine kinase or platelet-derived growth factor receptor-alpha (PDGFRA) germline mutations, but may also develop in the setting of type 1 neurofibromatosis. The molecular abnormalities of gastrointestinal stromal tumors arising in neurofibromatosis have not been extensively studied. We identified three...

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Share to Antigens, CD34
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

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Source

Identifiers

PMID: 15540118
DOI: 10.1038/modpathol.3800334

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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