Article
Epidermal growth factor binding sites on human erythrocytes in donors with different ABO blood groups.
American journal of hematology - 1 Apr 1992
Engelmann B, Schumacher U, Haen E
Abstract excerpt
Analysis of epidermal growth factor (125J-EGF) binding to human red cells revealed the presence of two classes of binding sites with apparent equilibrium dissociation constants (app.Kd) in the 10(-10)-10(-9) M and in the 10(-8) M range, respectively. The number of binding sites/cell ranged between 600 and 2,400 for the high-affinity binding site and between 7,200 and 23,000 for the low-affinity site. No...
Topics
- ABO Blood-Group System
- Binding Sites
- Blood Donors
- Epidermal Growth Factor
- ErbB Receptors
- Erythrocytes
- Genetic Variation
- Histocompatibility
- Humans
- Isoantigens
- Protein Binding