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Article

Test of the principle of initial value in rat genetic models of exercise capacity.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Feb 2005

Koch Lauren Gerard, Green Cheryl L, Lee Abraham D, Hornyak Joseph E, Cicila George T, Britton Steven L

Abstract excerpt

An inverse relationship between initial level of physical capacity and the magnitude of response to training is termed the principle of initial value. We tested the operation of this principle under experimental conditions of minimal genetic and environmental variation. Inbred rat strains previously identified as genetic models of low [Copenhagen (COP)] and high [Dark Agouti (DA)] intrinsic (untrained) exercise...

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PMID: 15528391
DOI: 10.1152/ajpregu.00621.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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