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Migration through host cells: the first steps of Plasmodium sporozoites in the mammalian host

4 Nov 2004

Abstract excerpt

Malaria starts with the infection of the liver by Plasmodium sporozoites. This form of the parasite migrates through several host cells breaching their plasma membranes before infecting a final hepatocyte which they enter forming a parasitophorous vacuole. It is still controversial why Plasmodium sporozoites migrate through host cells. By reviewing the most recent literature, we hope to give an insight on the...

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PMID: 15527491
DOI: 10.1111/j.1462-5822.2004.00460.x

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