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Article

Developmental roles of p73 in Cajal-Retzius cells and cortical patterning.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Nov 2004

Meyer Gundela, Cabrera Socorro Alfredo, Perez Garcia Carlos Gustavo, Martinez Millan Luis, Walker Nancy, Caput Daniel

Abstract excerpt

To examine the role of the p53 homolog p73 in brain development, we studied p73-/-, p73+/-, E2F1-/-, and reeler mutant mice. p73 in developing brain is expressed in Cajal-Retzius (CR) cells, the cortical hem, and the choroid plexus. p73-expressing CR cells are lost in p73-/- embryos, although Reelin is faintly expressed in the marginal zone. Ectopic neurons in the p73-/- preplate and cortical hem at embryonic day...

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Identifiers

PMID: 15525772
DOI: 10.1523/JNEUROSCI.3060-04.2004
PMCID: PMC6730229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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