Article
Analyses for binding of the transferrin family of proteins to the transferrin receptor 2.
British journal of haematology - 1 Nov 2004
Kawabata Hiroshi, Tong Xiangjun, Kawanami Takafumi, Wano Yuji, Hirose Yuko, Sugai Susumu, Koeffler H Phillip
Abstract excerpt
Transferrin receptor 2 alpha (TfR2 alpha), the major product of the TfR2 gene, is the second receptor for transferrin (Tf), which can mediate cellular iron uptake in vitro. Homozygous mutations of TfR2 cause haemochromatosis, suggesting that TfR2 alpha may not be a simple iron transporter, but a...
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