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Article

CD4+ Tregs and immune control.

The Journal of clinical investigation - 1 Nov 2004

Fehérvari Zoltán, Sakaguchi Shimon

Abstract excerpt

Recent years have seen Tregs become a popular subject of immunological research. Abundant experimental data have now confirmed that naturally occurring CD25+CD4+ Tregs in particular play a key role in the maintenance of self tolerance, with their dysfunction leading to severe or even fatal immunopathology. The sphere of influence of Tregs is now known to extend well beyond just the maintenance of immunological...

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Identifiers

PMID: 15520849
DOI: 10.1172/JCI23395
PMCID: PMC524236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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