Article
CD4+ Tregs and immune control.
The Journal of clinical investigation - 1 Nov 2004
Fehérvari Zoltán, Sakaguchi Shimon
Abstract excerpt
Recent years have seen Tregs become a popular subject of immunological research. Abundant experimental data have now confirmed that naturally occurring CD25+CD4+ Tregs in particular play a key role in the maintenance of self tolerance, with their dysfunction leading to severe or even fatal immuno...
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