Article
The nature of stem cells: state rather than entity.
Nature reviews. Genetics - 1 Nov 2004
Zipori Dov
Abstract excerpt
Stem cells are endowed with self-renewal and multipotential differentiation capacities. Contrary to the expectation that stem cells would selectively express specific genes, these cells have a highly promiscuous gene-expression pattern. Here, I suggest that the transient stem cell state, termed the 'stem state', may be assumed by any cell and that the search for specific genes expressed by all stem cells, which...
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