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Article

Nonsense suppression of the major rhodopsin gene of Drosophila.

Genetics - 1 Mar 1992

Washburn T, O'Tousa J E

Abstract excerpt

We placed UAA, UAG and UGA nonsense mutations at two leucine codons, Leu205 and Leu309, in Drosophila's major rhodopsin gene, ninaE, by site-directed mutagenesis, and then created the corresponding mutants by P element-mediated transformation of a ninaE deficiency strain. In the absence of a genetic suppressor, flies harboring any of the nonsense mutations at the 309 site, but not the 205 site, show increased...

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Identifiers

PMID: 1551579
DOI: 10.1093/genetics/130.3.585
PMCID: PMC1204875

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