Developmental arrest and ecdysteroid deficiency resulting from mutations at the dre4 locus of Drosophila.

doi:10.1093/genetics/130.3.555

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Article

Developmental arrest and ecdysteroid deficiency resulting from mutations at the dre4 locus of Drosophila.

Genetics - 1 Mar 1992

Sliter T J, Gilbert L I

Abstract excerpt

Loss-of-function mutations of the dre4 gene of Drosophila melanogaster caused stage-specific developmental arrest, the stages of arrest coinciding with periods of ecdysteroid (molting hormone) regulated development. Nonconditional mutations resulted in the arrest of larval development in the firs...

Topics

Animals
Drosophila melanogaster
Ecdysteroids
Genes, Lethal
Homozygote
Invertebrate Hormones
Kinetics
Larva
Metamorphosis, Biological
Mutation
Phenotype
Temperature

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