Article
A Drosophila p38 orthologue is required for environmental stress responses.
EMBO reports - 1 Nov 2004
Craig Caroline R, Fink Jill L, Yagi Yoshimasa, Ip Y Tony, Cagan Ross L
Abstract excerpt
The p38 mitogen-activated protein kinase (MAPK) cascade is an evolutionarily conserved signalling mechanism involved in processes as diverse as apoptosis, cell fate determination, immune function and stress response. Aberrant p38 signalling has been implicated in many human diseases, including heart disease, cancer, arthritis and neurodegenerative diseases. To further understand the role of p38 in these...
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