SP‐40,40, a protein involved in the control of the complement pathway, possesses a unique array of disulphide bridges

doi:10.1016/0014-5793(92)80330-j

Article

SP‐40,40, a protein involved in the control of the complement pathway, possesses a unique array of disulphide bridges

3 Feb 1992

Abstract excerpt

SP-40,40 is a two-chain serum protein which acts in vitro as a potent inhibitor of the assembly of the membrane attack complex of human complement. It contains 10 cysteine residues, the numbers and locations of which are conserved in several mammalian species. Evidence is presented that all the cysteine residues are involved in interchain (alpha-beta) disulphide bonds. There are no free cysteine residues. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

SP‐40,40, a protein involved in the control of the complement pathway, possesses a unique array of disulphide bridges

Abstract excerpt

Topics

Related research