Article
Recent advances in the diagnosis and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Human reproduction update - 1 Jan 2000
Forest Maguelone G
Abstract excerpt
Congenital adrenal hyperplasias (CAH) are inherited defects of cortisol biosynthesis. More than 90% of CAH are caused by 21-hydroxylase deficiency (21-OHD), found in 1:10 000 to 1:15 000 live births. Females with 'classical' 21-OHD, being exposed to excess androgens prenatally, are born with viri...
Topics
- Adrenal Hyperplasia, Congenital
- Body Height
- Dose-Response Relationship, Drug
- Female
- Fertility
- Genetic Counseling
- Glucocorticoids
- Heterozygote
- Humans
- Incidence
- Infant, Newborn
- Mineralocorticoids
- Mutation
- Neonatal Screening
- Obstetric Surgical Procedures
- Pregnancy
- Prenatal Diagnosis
- Steroid 21-Hydroxylase