Article
[Identification of tumor antigens: strategies and perspectives].
Praxis - 22 Sept 2004
Jäger D, Zippelius A, Knuth A
Abstract excerpt
The identification of tumor antigens is crucial for the development of antigen-specific immunotherapies in cancer. Ideal target antigens for immunotherapies have a tumor specific expresssion pattern. Antigen expresssion in solid tumors is typically heterogenous. Therefore an effective immunotherapy should target several antigens simultaneously (polyvalent vaccine). Here we discuss strategies how tumor antigens...
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