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Article

What causes sudden death in heart failure?

Circulation research - 15 Oct 2004

Tomaselli Gordon F, Zipes Douglas P

Abstract excerpt

Patients with heart failure experience a number of changes in the electrical function of the heart that predispose to potentially lethal cardiac arrhythmias. Action potential prolongation, the result of functional downregulation of K currents, and aberrant Ca2+ handling is a recurrent theme. Significant alterations in conduction and activation of a number of initially adaptive but ultimately maladaptive signaling...

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Source

Identifiers

PMID: 15486322
DOI: 10.1161/01.RES.0000145047.14691.db

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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