The Helicobacter pylori restriction endonuclease-replacing gene, hrgA, and clinical outcome: comparison of East Asia and Western countries.

doi:10.1023/b:ddas.0000042263.18541.ec

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Article

The Helicobacter pylori restriction endonuclease-replacing gene, hrgA, and clinical outcome: comparison of East Asia and Western countries.

Digestive diseases and sciences - 1 Sept 2004

Lu Hong, Graham David Y, Yamaoka Yoshio

Abstract excerpt

It has been suggested that the putative Helicobacter pylori virulence factor hrgA is the first disease-specific marker for an H. pylori-related disease, (i.e., development of gastric cancer in East Asia). Our aim was to test the hypothesis that the presence of hrgA has disease specificity. We examined 458 H. pylori isolates including 289 from East Asia and 169 from Western countries whose cagA and vacA genotypes...

Topics

Age Distribution
DNA Restriction Enzymes
DNA, Bacterial
Asia, Eastern
Female
Genes, Bacterial
Genetic Markers
Genotype
Helicobacter Infections
Helicobacter pylori
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Incidence

Male

Predictive Value of Tests

Probability

Prognosis

Risk Assessment

Sampling Studies

Source

Open in PubMed

Identifiers

PMID: 15481336
DOI: 10.1023/b:ddas.0000042263.18541.ec

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15481336-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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