Article
[Issues on association studies on complex diseases].
Yi chuan xue bao = Acta genetica Sinica - 1 May 2004
Yan Wei-Li, Gu Dong-Feng
Abstract excerpt
Association study is widely used in elucidating genetic basis of complex diseases such as cardiovascular diseases, type 2 diabetes, essential hypertension and obesity. Some issues were discussed in the review, which include defining and controlling of confounding effects, selection of candidate genes and single nucleotide polymorphisms (SNPs), application of intermediate phenotype and haplotype analyses as well...
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