Article
How to search for the role of gene-environment interactions for lipids in humans.
Italian heart journal : official journal of the Italian Federation of Cardiology - 1 Jan 2002
Kluft Cornelis
Abstract excerpt
To target the interventions to the requirements of the individuals we need to identify the genes and the alleles which show variations in response pattern. For example, a lipid-lowering diet is effective for most people, but not so for everyone. The search for genetic polymorphisms that affect the response of LDL cholesterol to diet in humans has been disappointing up till now, and is the first hurdle to take. In...
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