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Article

Characterization of the canine desmin (DES) gene and evaluation as a candidate gene for dilated cardiomyopathy in the Dobermann.

Gene - 13 Oct 2004

Stabej Polona, Imholz Sandra, Versteeg Serge A, Zijlstra Carla, Stokhof Arnold A, Domanjko-Petric Aleksandra, Leegwater Peter A J, van Oost Bernard A

Abstract excerpt

Canine-dilated cardiomyopathy (DCM) in dogs is a disease of the myocardium associated with dilatation and impaired contraction of the ventricles and is suspected to have a genetic cause. A missense mutation in the desmin gene (DES) causes DCM in a human family. Human DCM closely resembles the can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15475165
DOI: 10.1016/j.gene.2004.06.050

Genes

DES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15475165-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Characterization of the canine desmin (DES) gene and evaluation as a candidate gene for dilated cardiomyopathy in the Dobermann.PMID 15475165Read ↗

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Noncompaction cardiomyopathy is caused by a novel in‐frame desmin ( DES ) deletion mutation within the 1A coiled‐coil rod segment leading to a severe filament assembly defectSemantic proximity Read ↗

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The Desmin (DES) Mutation p.A337P Is Associated with Left-Ventricular Non-Compaction Cardiomyopathy.Semantic proximity Read ↗

Canine candidate genes for dilated cardiomyopathy: annotation of and polymorphic markers for 14 genes.Semantic proximity Read ↗

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Molecular insights into cardiomyopathies associated with desmin (DES) mutationsSemantic proximity Read ↗

Restrictive Cardiomyopathy is Caused by a Novel Homozygous Desmin (DES) Mutation p.Y122H Leading to a Severe Filament Assembly DefectSemantic proximity Read ↗

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A Prospective Genetic Evaluation of Familial Dilated Cardiomyopathy in the Doberman PinscherSemantic proximity Read ↗

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