Article
Caenorhabditis elegans UBC-2 functions with the anaphase-promoting complex but also has other activities.
Journal of cell science - 15 Oct 2004
Frazier Tyralynn, Shakes Diane, Hota Uma, Boyd Lynn
Abstract excerpt
The anaphase-promoting complex or cyclosome (APC/C) is a multi-subunit ubiquitin ligase that regulates the eukaryotic cell cycle. APC/C belongs to the RING finger class of ubiquitin ligases that function by interacting with a ubiquitin-conjugating enzyme (Ubc), thus inciting the Ubc to transfer ubiquitin onto a target protein. Extensive studies with APC/C in other organisms have identified several possible Ubcs...
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