Article
Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis.
The Journal of biological chemistry - 17 Dec 2004
Okumura Fumihiko, Hatakeyama Shigetsugu, Matsumoto Masaki, Kamura Takumi, Nakayama Keiichi I
Abstract excerpt
E4B (also known as UFD2a) is a mammalian homolog of Saccharomyces cerevisiae Ufd2, which was originally described as a ubiquitin chain assembly factor (E4). E4B is a U-box-type ubiquitin-protein isopeptide ligase (E3) and likely functions as either an E3 or an E4. With a yeast two-hybrid screen,...
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