Article
The effect of dietary fat on LDL size is influenced by apolipoprotein E genotype in healthy subjects.
The Journal of nutrition - 1 Oct 2004
Moreno Juan Antonio, Pérez-Jiménez Francisco, Marín Carmen, Gómez Purificación, Pérez-Martínez Pablo, Moreno Rafael, Bellido Cecilia, Fuentes Francisco, López-Miranda José
Abstract excerpt
LDL particle size is dependent on both genetic factors and environmental factors such as dietary fat composition. The apolipoprotein E (apoE) genotype is a major genetic determinant of LDL size. Thus, the aim of this work was to study whether the apoE genotype interacts with the quantity and quality of dietary fat, modifying LDL size in young healthy subjects. Healthy subjects (n = 84; 66 apoE 3/3, 8 apoE 4/3, 10...
Topics
- Adult
- Apolipoproteins E
- Cholesterol, LDL
- Cross-Over Studies
- Dietary Carbohydrates
- Dietary Fats
- Fatty Acids
- Fatty Acids, Monounsaturated
- Female
- Genotype