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Article

Glutathione precursors replenish decreased glutathione pool in cystinotic cell lines.

Biochemical and biophysical research communications - 5 Nov 2004

Chol Marie, Nevo Nathalie, Cherqui Stéphanie, Antignac Corinne, Rustin Pierre

Abstract excerpt

Cystinosis is an inherited disorder due to mutations in the CTNS gene which encodes cystinosin, a lysosomal transmembrane protein involved in cystine export to the cytosol. Both accumulation of cystine in the lysosome and decreased cystine in the cytosol may participate in the pathogenic mechanis...

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Source

Identifiers

PMID: 15465007
DOI: 10.1016/j.bbrc.2004.09.033

Genes

CTNS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15465007-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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