Article
Leptin effect on intestinal galactose absorption in ob/ob and db/db mice.
Journal of physiology and biochemistry - 1 Jun 2004
Iñigo C, Barber A, Lostao M P
Abstract excerpt
Our previous works demonstrated that leptin inhibits galactose absorption in rat and mice intestinal rings. Here, we have studied the effect of exogenous leptin on intestinal galactose absorption in the genetically obese db/db (leptin-resistant) and ob/ob (leptin-deficient) mice. Assays were performed by incubating the intestinal rings in saline solution containing 5 mM galactose in the absence or presence of 0.2...
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