Article
Diversity of human immunodeficiency virus type 1 subtype A and CRF03_AB protease in Eastern Europe: selection of the V77I variant and its rapid spread in injecting drug user populations.
Journal of virology - 1 Oct 2004
Roudinskii Nikita I, Sukhanova Anna L, Kazennova Elena V, Weber Jonathan N, Pokrovsky Vadim V, Mikhailovich Vladimir M, Bobkov Aleksei F
Abstract excerpt
To characterize polymorphisms of the subtype A protease in the former Soviet Union, proviral DNA samples were obtained, with informed consent, from 119 human immunodeficiency virus type 1 (HIV-1)-positive untreated injecting drug users (IDUs) from 16 regions. All individuals studied have never been treated with antiretroviral drugs. The isolates were defined as IDU-A (n = 115) and CRF03_AB (n = 4) by using...
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