Article
Malignant lymphoma of mucosa-associated lymphoid tissue arising in the thymus of a patient with Sjögren's syndrome. A morphologic, phenotypic, and genotypic study.
Cancer - 15 Mar 1992
Takagi N, Nakamura S, Yamamoto K, Kunishima K, Takagi I, Suyama M, Shinoda M, Sugiura T, Oyama A, Suzuki H
Abstract excerpt
A 59-year-old woman with Sjögren's syndrome had an anterior mediastinal tumor. The tumor had epithelium-lined thymic cysts. Histologically, centrocyte-like (CCL) cells were present as clusters intermingling with small lymphocytes and plasma cells, invaded the epithelium, and formed characteristic lymphoepithelial lesions; the tumor was identified as malignant lymphoma arising in mucosa-associated lymphoid tissue...
Topics
- Cytoplasm
- Female
- Gene Rearrangement, B-Lymphocyte
- Genotype
- Humans
- Immunoglobulin A
- Immunoglobulin Light Chains
- Immunoglobulin kappa-Chains
- Lymphoid Tissue
- Lymphoma, B-Cell