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Article

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots

22 Sept 2004

Abstract excerpt

Fat depots vary in function and size. The preadipocytes that fat cells develop from exhibit distinct regional characteristics that persist in culture. Human abdominal subcutaneous cultured preadipocytes undergo more extensive lipid accumulation, higher adipogenic transcription factor expression, and less TNF-alpha-induced apoptosis than omental preadipocytes. We found higher replicative potential in subcutaneous...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 15383371
DOI: 10.1152/ajpendo.00265.2004

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