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Article

Overexpression of the Ets-1 transcription factor in human breast cancer

7 Sept 2004

Abstract excerpt

The Ets family of transcription factors regulate expression of multiple genes involved in tumour progression. The aim of this study was to investigate the expression of Ets-1 in a large panel of human breast cancers and relate its levels to the parameters of tumour progression and metastasis. Using RT-PCR, Ets-1 mRNA was detected in 30 out of 42 (71%) fibroadenomas and 131 out of 179 (73%) primary breast...

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PMID: 15365563
DOI: 10.1038/sj.bjc.6602128

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