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Non‐immunostimulatory nonviral vectors

13 Sept 2004

Abstract excerpt

The vectors for gene delivery are usually classified as viral and nonviral vectors. While the viral vectors are very efficient in transducing cells, safety concerns regarding their use in humans make nonviral vectors an attractive alternative. Among the nonviral vectors, the lipoplexes (complexes of cationic liposome/pDNA) are the most studied and represent the most promising approaches for human clinical trials....

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PMID: 15364893
DOI: 10.1096/fj.04-2187fje

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