Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products

Abstract excerpt

Although most research on gene therapy has focused on the use of recombinant viruses to deliver genes to cells in vivo, progress also has been made toward developing nonviral, pharmaceutical formulations of genes for in vivo human therapy. Various methods for nonviral gene therapy have been proposed. Some approaches are aimed at developing “artificial viruses” that attempt to mimic the process of viral infection...

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