Article
In vitro activity of fluoroquinolone and the gyrA gene mutation in Helicobacter pylori strains isolated from children.
Journal of medical microbiology - 1 Oct 2004
Fujimura Shigeru, Kato Seiichi, Iinuma Kazuie, Watanabe Akira
Abstract excerpt
Resistance to antibiotics, especially clarithromycin, is the major cause of the failure to eradicate Helicobacter pylori. There are few studies in children concerning fluoroquinolone activity against H. pylori. Primary resistance to antibiotics including fluoroquinolones was studied in 55 H. pylori strains isolated from Japanese children. DNA sequences of the gyrA gene in fluoroquinolone-resistant strains were...
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