Article
The potential clinical and economic outcomes of pharmacogenetics-oriented management of warfarin therapy - a decision analysis.
Thrombosis and haemostasis - 1 Sept 2004
You Joyce H S, Chan Fredric W H, Wong Raymond S M, Cheng Gregory
Abstract excerpt
Variant cytochrome P450 (CYP) 2C9 genotypes are associated with low maintenance dose requirement of warfarin therapy and increased risk of major bleeding events. The objective of the present study was to evaluate the potential clinical and economic outcomes of using CYP2C9 genotype data to guide the management of anticoagulation therapy and to identify influential factors affecting the cost-effectiveness of this...
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