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Article

Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies.

The International journal of developmental biology - 1 Jan 2004

Folgueras Alicia R, Pendás Alberto M, Sánchez Luis M, López-Otín Carlos

Abstract excerpt

Over the last years, the relevance of the matrix metalloproteinase (MMP) family in cancer research has grown considerably. These enzymes were initially associated with the invasive properties of tumour cells, owing to their ability to degrade all major protein components of the extracellular matrix (ECM) and basement membranes. However, further studies have demonstrated the implication of MMPs in early steps of...

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PMID: 15349816
DOI: 10.1387/ijdb.041811af

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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