Article
A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana.
Proceedings of the National Academy of Sciences of the United States of America - 14 Sept 2004
Zhang Peng, Chomel Bruno B, Schau Maureen K, Goo Jeanna S, Droz Sara, Kelminson Karen L, George Smitha S, Lerche Nicholas W, Koehler Jane E
Abstract excerpt
Bartonella species are fastidious, Gram-negative human pathogens that can persist in the host bloodstream for years and bind to and invade several types of host cells. For many pathogens, adhesion to host cells and extracellular matrix (ECM) components is a critical virulence determinant. Bacteria often vary expression of surface adhesins by phase or antigenic variation to subvert the host immune response and...
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