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Article

Evidence for multiple alleles at the DGAT1 locus better explains a quantitative trait locus with major effect on milk fat content in cattle.

Genetics - 1 Aug 2004

Kühn Christa, Thaller Georg, Winter Andreas, Bininda-Emonds Olaf R P, Kaupe Bernhard, Erhardt Georg, Bennewitz Jörn, Schwerin Manfred, Fries Ruedi

Abstract excerpt

A quantitative trait locus (QTL) for milk fat percentage has been mapped consistently to the centromeric region of bovine chromosome 14 (BTA14). Two independent studies have identified the nonconservative mutation K232A in the acylCoA-diacylglycerol-acyltransferase 1 (DGAT1) gene as likely to be causal for the observed variation. Here we provide evidence for additional genetic variability at the same QTL that is...

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Source

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Identifiers

PMID: 15342525
DOI: 10.1534/genetics.103.022749
PMCID: PMC1470998

Genes

DGAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for multiple alleles at the DGAT1 locus better explains a quantitative trait locus with major effect on milk fat content in cattle.PMID 15342525Read ↗

Alleles of the bovine DGAT1 variable number of tandem repeat associated with a milk fat QTL at chromosome 14 can stimulate gene expression.Semantic proximity Read ↗

The DGAT1 K232A mutation is not solely responsible for the milk production quantitative trait locus on the bovine chromosome 14.Semantic proximity Read ↗

Effects of DGAT1 variants on milk production traits in German cattle breeds.Semantic proximity Read ↗

Characterization of the DGAT1 K232A and variable number of tandem repeat polymorphisms in French dairy cattle.Semantic proximity Read ↗

DGAT1 polymorphism in Bos indicus and Bos taurus cattle breeds.Semantic proximity Read ↗

Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content.Semantic proximity Read ↗

Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition.Semantic proximity Read ↗

Characterization of the DGAT1 mutations and the CSN1S1 promoter in the German Angeln dairy cattle population.Semantic proximity Read ↗

Dominance and parent-of-origin effects of coding and non-coding alleles at the acylCoA-diacylglycerol-acyltransferase (DGAT1) gene on milk production traits in German Holstein cows.Semantic proximity Read ↗

DGAT1 K232A polymorphism in Brazilian cattle breeds.Semantic proximity Read ↗

Novel SNPs and INDEL polymorphisms in the 3'UTR of DGAT1 gene: in silico analyses and a possible association.Semantic proximity Read ↗

DGAT1 and ABCG2 polymorphism in Indian cattle (Bos indicus) and buffalo (Bubalus bubalis) breeds.Semantic proximity Read ↗

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