Article
Novel SNPs and INDEL polymorphisms in the 3'UTR of DGAT1 gene: in silico analyses and a possible association.
Molecular biology reports - 1 Jul 2014
Rosse Izinara da Cruz, Steinberg Raphael da Silva, Coimbra Roney Santos, Peixoto Maria Gabriela Campolina Diniz, Verneque Rui Silva, Machado Marco Antonio, Fonseca Cleusa Graça, Carvalho Maria Raquel Santos
Abstract excerpt
Diacylglycerol-O-acyltransferase (DGAT1) gene encodes the rate-limiting enzyme of triglyceride synthesis. A polymorphism in this gene, DGAT1 K232A, has been associated with milk production and composition in taurine breeds. However, this polymorphism is not a good tool for ascertaining the effects of this QTL in Bos indicus (Zebu), since the frequency of the DGAT1 232A allele is too low in these breeds. We...
Topics
- 3' Untranslated Regions
- Animals
- Breeding
- Cattle
- Computer Simulation
- Diacylglycerol O-Acyltransferase
- Female
- Gene Expression
- Genotype
- Glycolipids