Article
Recognition of Leishmania antigens by T lymphocytes from nonexposed individuals.
Infection and immunity - 1 Jun 1992
Kemp M, Hansen M B, Theander T G
Abstract excerpt
Crude antigen preparations of Leishmania promastigote sonicates were found to induce in vitro proliferation and gamma interferon production in peripheral blood mononuclear cells (PBMC) from individuals without known exposure to the parasite. The proliferating cells were mainly CD2-positive T cells. The proliferative response was maximal after more than 6 days of incubation with the antigens in contrast to the...
Topics
- Adult
- Animals
- Antigens, CD
- Antigens, Protozoan
- DNA
- Histocompatibility Antigens
- Humans
- Interferon-gamma
- Leishmania
- Leukocyte Common Antigens
- Lymphocyte Activation
- Phenotype