Article
Immunoregulatory effects of Borrelia burgdorferi on T-B cell interactions.
The Journal of rheumatology - 1 Apr 1992
Goronzy J J, Hanson T L, Weyand C M
Abstract excerpt
Late stages of Lyme borreliosis are characterized by a disproportionate inflammatory response presumably elicited by only minute amounts of persisting antigen. To explore the possibility that amplification mechanisms of the immune response shape disease manifestations, we studied immunoregulatory properties of Borrelia burgdorferi antigens and analyzed whether they influence B cell-T cell cooperation. B....
Topics
- Antigen-Presenting Cells
- Antigens, Bacterial
- B-Lymphocytes
- Borrelia burgdorferi Group
- Cell Communication
- Cell Division
- Cells, Cultured
- Epitopes
- Humans
- Immunity
- Lyme Disease
- Phenotype