Article
Immunomagnetic removal of neurons from developing chick optic tectum results in glial phenotypic instability.
Glia - 1 Jan 1992
Galileo D S, Linser P J
Abstract excerpt
The ability of embryonic day 12 and 13 optic tectum cells to replace depleted A2B5(+) cells and neurons was tested by immunomagnetic cell separation. Nearly all purified surface A2B5(-) cells were identified as glia by immunoreactivity for either glutamine synthetase of galactocerebroside. Most (approximately 80%) of the purified A2B5(-) cells became A2B5(+) after 1 day in culture, although no increase in the...
Topics
- Animals
- Astrocytes
- Cell Adhesion
- Chick Embryo
- Glial Fibrillary Acidic Protein
- Magnetics
- Neuroglia
- Neurons
- Oligodendroglia
- Phenotype
- Radioimmunoassay
- Superior Colliculi