Use of gene replacement transformation to elucidate gene function in the qa gene cluster of Neurospora crassa.

doi:10.1093/genetics/130.4.729

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Article

Use of gene replacement transformation to elucidate gene function in the qa gene cluster of Neurospora crassa.

Genetics - 1 Apr 1992

Case M E, Geever R F, Asch D K

Abstract excerpt

Gene replacement by transformation, employing selective genetic recombination techniques, has been used to delete or disrupt the qa-x, qa-y and qa-1S genes of the qa gene cluster of Neurospora crassa. The growth characteristics of the strain carrying the deletion of the qa-y gene support earlier...

Topics

Chromosome Deletion
Genes, Fungal
Multigene Family
Mutation
Neurospora crassa
Quinic Acid
Transformation, Genetic

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