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Article

Familial concordance of phenotype and microbial variation among siblings with CF.

Pediatric pulmonology - 1 Oct 2004

Picard Elie, Aviram Micha, Yahav Yaakov, Rivlin Joseph, Blau Hanna, Bentur Lea, Avital Avraham, Villa Yael, Schwartz Shepard, Kerem Batsheva, Kerem Eitan

Abstract excerpt

The clinical spectrum of cystic fibrosis (CF) is influenced by the cystic fibrosis transmembrane conductance regulator (CFTR) genotype. However, variable courses of the disease were demonstrated among patients with identical genotypes. Since siblings share identical CFTR mutations and environmental factors, they can serve as a model to assess the effect of modifier genes on disease expression, and also to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15334505
DOI: 10.1002/ppul.20111

Genes

CFTR
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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