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Article

Evaluation of clinical concordance in FMF siblings with identical biallelic exon 10 variants.

Postgraduate medicine - 1 Mar 2026

Tunce Eray, Öz Mahmut Seyfeddin, Atamyıldız Uçar Sıla, Sözeri Betül

Abstract excerpt

OBJECTIVES: To evaluate the extent of clinical concordance and phenotypic variability among pediatric FMF sibling pairs carrying identical biallelic exon 10 MEFV variants. METHODS: This cross-sectional study included 194 pediatric FMF patients from 97 families, all harboring identical biallelic pathogenic exon 10 variants. After excluding four monozygotic twin patients from two families, 190 non-twin siblings...

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Source

Identifiers

PMID: 41766089
DOI: 10.1080/00325481.2026.2638010

Genes

MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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