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Article

Lack of association between hypermutation and antibiotic resistance development in Pseudomonas aeruginosa isolates from intensive care unit patients.

Antimicrobial agents and chemotherapy - 1 Sept 2004

Gutiérrez Olivia, Juan Carlos, Pérez José L, Oliver Antonio

Abstract excerpt

Hypermutation is a common feature of Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients that is linked with antibiotic resistance development. In this work, using a large collection of sequential P. aeruginosa isolates from ICU patients, we found that despite the fact that mutational antibiotic resistance development is a frequent outcome, the prevalence of hypermutable strains is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15328130
DOI: 10.1128/AAC.48.9.3573-3575.2004
PMCID: PMC514756

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