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Article

Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations.

Antimicrobial agents and chemotherapy - 1 Sept 2004

Stevens David A, Espiritu Marife, Parmar Rachana

Abstract excerpt

Resistance problems with caspofungin, an echinocandin inhibitor of fungal cell wall glucan synthesis, have been rare. We noted paradoxical turbid growth of Candida albicans isolates in broth in some high (supra-MIC) concentrations. Among isolates submitted for susceptibility testing and screened...

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Identifiers

PMID: 15328104
DOI: 10.1128/AAC.48.9.3407-3411.2004
PMCID: PMC514730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15328104-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations.PMID 15328104Read ↗

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