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Article

Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

Neurology - 24 Aug 2004

Münch C, Sedlmeier R, Meyer T, Homberg V, Sperfeld A D, Kurt A, Prudlo J, Peraus G, Hanemann C O, Stumm G, Ludolph A C

Abstract excerpt

The authors report mutation screening of the p150 subunit of dynactin (DCTN1) and the cytoplasmic dynein heavy chain (DNCHC1) genes in 250 patients with ALS and 150 unrelated control subjects. Heterozygous missense mutations of the DCTN1 gene were detected in one apparently sporadic case of ALS (...

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Share to Amyotrophic Lateral Sclerosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15326253
DOI: 10.1212/01.wnl.0000134608.83927.b1

Genes

DCTN1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15326253-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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