Article
Efficient co-expression of a recombinant staphopain A and its inhibitor staphostatin A in Escherichia coli.
The Biochemical journal - 1 Jan 2005
Wladyka Benedykt, Puzia Katarzyna, Dubin Adam
Abstract excerpt
Staphopain A is a staphylococcal cysteine protease. Genes encoding staphopain A and its specific inhibitor, staphostatin A, are localized in an operon. Staphopain A is an important staphylococcal virulence factor. It is difficult to perform studies on its interaction with other proteins due to problems in obtaining a sufficient amount of the enzyme from natural sources. Therefore efforts were made to produce a...
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