Article
T lymphocytes in human atherosclerotic plaques are memory cells expressing CD45RO and the integrin VLA-1.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Feb 1992
Stemme S, Holm J, Hansson G K
Abstract excerpt
The cellular composition of human atherosclerotic plaques has been analyzed in several immunohistochemical studies in recent years. These studies have shown that the main cell types of the plaque are macrophages, smooth muscle cells, and T lymphocytes. To further characterize the T-lymphocyte population in atherosclerotic plaques, human plaque tissue was digested enzymatically and the released cells were labeled...
Topics
- Aged
- Antigens
- Antigens, CD
- Arteriosclerosis
- Female
- Histocompatibility Antigens
- Humans
- Immunologic Memory
- Integrins
- Leukocyte Common Antigens
- Lymphocyte Activation
