Article
Insulin-Sperm Interaction: Effects on Plasma Membrane and Binding to Acrosome
1 Jan 1992
Abstract excerpt
In in vitro studies, viable, intact human spermatozoa took up free radioinsulin with an apparently non-receptor-mediated mechanism. However, when a colloidal gold-insulin complex was substituted for the radiotracer, no surface binding was visualized at the ultrastructural level. Upon sperm incubation in the presence of free insulin, a dose-dependent release of phospholipid phosphorus occurred, with a concomitant...
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